Platform & software · Nuclear medicine software

Nuclear medicine software compared across PET CT software, nuclear medicine reporting and processing vendors

The short answer

Nuclear medicine software is three separate purchases that share a name. The first is processing and reading software, which reconstructs, fuses and quantifies PET/CT and SPECT/CT studies: MIM Software, now owned by GE HealthCare, and Hermes Medical Solutions are the two vendor-neutral names, alongside the console suites each scanner maker ships. The second is the department information system, usually called an NMIS, which tracks radiopharmaceutical doses from receipt to disposal and produces the records an NRC or agreement-state inspector asks for. The third is reporting, where the physician turns SUV measurements and comparison reads into a signed report. Checked against openFDA on September 17, 2026, MIM holds 22 FDA 510(k) clearances and Hermes holds 17, while the NMIS products hold none because they manage records rather than images. Federal contract awards put a MIM or Hermes system between about $50,000 and $750,000 depending on scope, and an NMIS site license at a median of $17,580.

Nuclear medicine departments buy software in a market that is small enough to have almost no independent comparison in it. Search the category and the first page is the vendors themselves, a market research abstract and a product directory. That is fine for finding names and useless for choosing between them, because the names do different jobs.

A processing suite is the workstation the physician reads on. It takes the raw PET, SPECT and CT series off the camera, reconstructs and registers them, fuses the functional image onto the anatomy and produces the numbers that end up in the report: SUVmax and SUVpeak, lesion volumes, Deauville and PERCIST assessments, cardiac perfusion scores, dosimetry for radionuclide therapy. That is regulated software. It changes what the physician sees and measures, so it clears through the FDA 510(k) process under the image processing regulation at 21 CFR 892.2050 or the emission tomography regulation at 892.1200.

A nuclear medicine information system is a different thing entirely. It records which unit dose arrived from which radiopharmacy, its assayed activity and time, which patient received it and when, what was left over, and how the residual was decayed and disposed of. It holds the wipe test results, the dose calibrator constancy checks, the receiving surveys and the sealed source inventory. When an inspector visits, the NMIS is what gets opened. None of this touches an image, so none of it needs a clearance.

Reporting sits on top of both and is where the department's time actually goes. A whole-body PET/CT report in an oncology practice runs to several hundred words, carries a table of measurements against a prior study, and has to reconcile the nuclear medicine physician's read of the functional data with the diagnostic CT read that often comes from a different radiologist. Most groups still dictate that from scratch.

This page separates the three layers, puts the verifiable facts about each vendor side by side, and is honest about where Radiological.ai fits. It is not a nuclear medicine processing system and does not reconstruct, fuse or quantify PET or SPECT data. It reads X-ray, CT and MRI, and where it touches this category is the CT component of a PET/CT and the structured report the department signs.

The Reading Station

Assistant ready

Worklist

Not for diagnostic use

Structured report

Draft

Run the assistant to draft this report for review.

You review & sign

Decision support. The radiologist reviews and signs every study.

Drafted in · you review & sign Worklist re-prioritized

Decision support for qualified clinicians. Radiological.ai does not provide a diagnosis and is not a substitute for professional judgment.

Run the assistant

Flag · prioritize · draft · you review and sign

X-RAY CT MRI BUILT WITH RADIOLOGISTS

Decision support not a diagnosis

You review & sign

Processing software hands its images and measurements to the archive over the same interfaces as every other modality, so the integration questions are the ones in radiology PACS integration, DICOM and HL7, and which archive holds them is worked through in PACS software and PACS system vendors compared by study volume and enterprise imaging and vendor neutral archive software. Orders, scheduling and the exam record live in the radiology information system, which the NMIS usually talks to over an HL7 interface.

The report is where the measurements end up, so the template design questions in structured radiology reporting apply directly to PET/CT, and the radiology reporting software comparison covers the dictation and drafting products the department will read into. CT dose recorded on the CT half of a hybrid study follows the same rules as any other CT, covered in radiation dose monitoring software. For what the surrounding software costs against federal contract data, see radiology software pricing, and for the department-system layer specifically, the nuclear medicine information system buyer's guide compares NMIS, IBC and Optility on cost and compliance records.

Side by side

Five nuclear medicine software products, compared on what can be verified

The first three columns are processing and reading software. The fourth is the scanner maker's own suite. The fifth is a department information system, which is a different layer and is here because buyers keep comparing it to the others.

What you are comparing	MIM Software (GE HealthCare)	Hermes Medical Solutions	Segami Oasis	OEM console suites	ec2 NMIS and BioDose (Mirion)
Which layer it is	Vendor-neutral processing, quantification and dosimetry across PET, SPECT and CT	Vendor-neutral processing, reading and dosimetry, plus a nuclear medicine PACS	Vendor-neutral processing and viewing	Processing and reading tied to the maker's scanners, for example Siemens syngo.via and GE Xeleris	Department information system: dose tracking, hot lab records, compliance reports. Not an image tool
FDA 510(k) clearances held by the applicant	22, from Mobile MIM in February 2011 to Contour ProtégéAI+ in March 2026	17, from the Hermes Medical Imaging Suite in December 2012 to Affinity in July 2026	6, from Mirage in October 1997 to Oasis Release 1.0 in August 2007	Cleared with, or as accessories to, the scanner	None, and none required. It manages records rather than images
Most recent nuclear medicine clearance	MIM LesionID Pro, K251883, December 11, 2025, code LLZ	Affinity, K253835, July 31, 2026, code QIH; Hybrid Viewer, K252477, September 9, 2025, code KPS	Oasis Release 1.0, K071584, August 31, 2007. Nothing since	Varies by scanner generation	Not applicable
Who owns it	GE HealthCare, which acquired MIM Software on April 1, 2024 for about $258 million net of cash plus up to $35 million in milestones	Independent, headquartered in Stockholm, with a United States subsidiary that holds the federal contracts	Independent, Columbia, Maryland	Siemens Healthineers, GE HealthCare, Philips	Mirion Technologies, which acquired ec2 Software Solutions and NUMA on November 1, 2023 for $33 million in cash
Federal prime contract awards found	236 awards, 2008 to 2026, $15,473,497 in total	73 awards, 2007 to 2026, $7,433,790 in total	1 award, $33,375, June 2010	Bundled into scanner purchases; not separable	67 software and support awards, 2007 to 2026, $1,641,247 in total
Median federal award	$34,837	$64,543	No basis	No basis	$17,580
Largest federal award seen	$1,334,090, VA, "Nuclear Med Integrated Platform", September 2023	$749,500, Army, nuclear medicine hardware and software, May 2017	$33,375	Not separable	$169,479, VISN 10 BioDose, September 2023; $162,597 BioDose Enterprise upgrade, May 2026
Who buys it in the public record	VA medical centers overwhelmingly, plus the Defense Health Agency, the Navy and NIH; most awards are radiation oncology contouring, 25 name nuclear medicine, Encore, PET, SPECT or Y90	Army, Defense Health Agency and VA; 37 of the 73 awards started in 2025 or 2026	One Defense Logistics Agency capital equipment purchase	Every scanner buyer, by default	VA sites almost entirely, bought direct from Mirion (Capintec) in 31 awards and through Mystic Ventures Group, Pinestar Technology and Pulcir in the rest
The honest case against it	You now buy vendor-neutral software from a scanner vendor, and the acquisition is recent enough that the roadmap is still being set	Smaller company than the OEMs, and the federal surge is recent, so ask for reference sites of your own size	No new clearance in nineteen years is a question to put to the vendor before anything else	Ties your reading workstation to your camera contract, which is the point of buying vendor-neutral	Solves the hot lab and the inspection, and nothing about reading or reporting; do not compare it to the first four columns

FDA counts are 510(k) records returned by the openFDA device endpoint for each applicant name on September 17, 2026. Federal award figures are prime contract awards from USAspending.gov retrieved the same day, with every recipient name and award description read individually before it was counted; MIM and Hermes figures are for the recipient as a whole and include radiation oncology and maintenance awards, and the NMIS figures exclude label paper, parts and any award under $1,000. A zero means no record matched, not that the product is unavailable. Ownership and product scope change; confirm current products and pricing with the vendor before shortlisting.

Why it works

What your group gets with nuclear medicine software

The FDA record separates the reading vendors, and it says nothing about the NMIS

Searched by applicant on September 17, 2026, openFDA returns 22 clearances for MIM Software, 17 for Hermes Medical Solutions, 6 for Segami, 4 for EXINI Diagnostics, whose aPROMISE PET analysis is now part of Lantheus, and 10 for Mirada Medical. The dates are the useful part. MIM cleared LesionID Pro in December 2025 and two dosimetry products in 2024. Hermes cleared Affinity in July 2026 and Hybrid Viewer in September 2025. Segami's most recent clearance is Oasis Release 1.0 from August 2007. A vendor can update cleared software without a new submission, so an old date is not proof of an old product, but it is the first question to ask. The department information systems have no clearances at all, and a procurement scorecard that docks them for it has misunderstood what they are.

Real prices run from a $17,580 NMIS license to a $1.3 million integrated platform

Federal awards are the only public price record in this category. For the department system, 67 software and support awards for NMIS and BioDose between 2007 and 2026 total $1,641,247 with a median of $17,580, and 45 of the 67 fall between $10,000 and $50,000; the two outliers are a $169,479 VISN 10 BioDose award in September 2023 and a $162,597 BioDose Enterprise upgrade in May 2026. Since 2023 the median has risen to $24,518 across 18 awards. For reading software, Hermes' 73 awards have a median of $64,543 and top out at $749,500, and MIM's 236 awards have a median of $34,837 and top out at $1,334,090 for a VA nuclear medicine integrated platform in September 2023. A single Hermes nuclear medicine PACS award in June 2022 was $499,995, and a two-site MIM post-processing subscription in July 2023 was $624,763. Read these as scale for specific scopes, not list prices, and note that many are annual maintenance rather than new purchases.

The report is the layer nobody sells you, and it is where the hours go

Processing software produces the numbers. The NMIS produces the compliance record. Neither produces the report, and a whole-body PET/CT report with a measurement table against the prior study is among the longest documents a radiology department signs. Radiological.ai is not nuclear medicine processing software and does not reconstruct, fuse or quantify PET or SPECT data. It supports X-ray, CT and MRI. Where it fits a hybrid imaging department is the CT half of the PET/CT, which it reads for suspected findings and prioritizes on the worklist like any other CT, and the structured report, which it drafts into the department's own template so the SUV table, the comparison fields and the impression land in the same place on every study. The physician enters the functional read, reviews everything, edits and signs.

What it handles

Flagged, prioritized and drafted for your review

The assistant pre-reads each study, surfaces a region of interest for review, re-prioritizes the worklist, and drafts the structured report in your template. You confirm, edit and sign.

Flags suspected findings on the CT component of a PET/CT for a second look before the report is signed
Prioritizes the worklist so urgent hybrid studies are read first
Drafts the structured report into your own PET/CT and SPECT templates, with the measurement table and comparison fields in fixed positions
Keeps report structure consistent across nuclear medicine physicians and radiologists who share a study
Works alongside MIM, Hermes or your OEM suite and your NMIS rather than replacing any of them
Physician reviews, edits and signs every study

NUCLEAR MEDICINE SOFTWARE STAT

Region of interest flagged for review

A focal region is surfaced on the sample study for the radiologist to review. The assistant does not characterize it as a diagnosis.

Draft impression

Suspected finding flagged for radiologist review. Correlate clinically and confirm. Draft for review and sign-off.

Decision support · not for diagnostic use You review & sign

Why Radiological.ai

One assistant across the whole read

Not three vendors stitched together. Flag, prioritize and draft in one calm pane, on X-ray, CT and MRI, with the radiologist signing every study.

Flags suspected findings

A second set of eyes surfaces regions of interest for review on every study, so a suspected finding is less likely to slip past late in a shift.

Prioritizes the worklist

Suspected-critical studies move to the top, so urgent reads surface ahead of routine follow-ups across your sites and shifts.

Drafts the report

A structured draft arrives in your template, ready to edit and sign. The draft saves the typing and the measuring, never the judgment.

Good questions

Questions about nuclear medicine software

Three kinds. Processing and reading software reconstructs, fuses and quantifies PET/CT and SPECT/CT studies; MIM Software, Hermes Medical Solutions and the scanner makers' own suites such as Siemens syngo.via and GE Xeleris are the main names. A nuclear medicine information system such as ec2 NMIS or BioDose tracks radiopharmaceutical doses and produces inspection records. Reporting software, whether dictation or AI drafting, turns the measurements into the signed report.

NMIS stands for Nuclear Medicine Information System. It is department management software that records every radiopharmaceutical dose from receipt through administration to decay and disposal, keeps the dose calibrator, wipe test and survey records, and prints the reports an NRC or agreement-state inspector asks for. The best-known product carries the name NMIS itself, created in 1985 and now sold by Mirion after its 2023 acquisition of ec2 Software Solutions. It does not process or display images.

MIM Software is vendor-neutral medical image processing software used in nuclear medicine, radiology, radiation oncology and molecular radiotherapy. Its nuclear medicine products cover PET/CT and SPECT/CT fusion and quantification, cardiac analysis and dosimetry for radionuclide therapy. The company holds 22 FDA 510(k) clearances dating from 2011 and has been owned by GE HealthCare since April 1, 2024, when it was acquired for about $258 million net of cash.

Processing and reading software is FDA cleared rather than approved, through the 510(k) route, because it changes what the physician sees and measures. On September 17, 2026, openFDA shows 22 clearances for MIM Software and 17 for Hermes Medical Solutions, most under product codes LLZ, QIH and KPS. Department information systems such as NMIS and BioDose hold no clearances and need none, because they manage dose records and inventory rather than images.

Federal contract awards are the only public price record. An NMIS or BioDose site license and support has a median award of $17,580 across 67 awards since 2007, with most between $10,000 and $50,000. Hermes awards have a median of $64,543 and run to $749,500 for a full hardware and software installation. MIM awards have a median of $34,837 and run to $1,334,090 for a VA integrated nuclear medicine platform. Annual maintenance is usually quoted separately.

Hermes Medical Solutions is an independent Stockholm company whose Hermia suite covers PET/CT, SPECT/CT and PET/MR reading, quantification and voxel dosimetry, and which also sells a nuclear medicine PACS. It holds 17 FDA clearances, the most recent being Affinity on July 31, 2026 and Hybrid Viewer on September 9, 2025. Its United States subsidiary holds 73 federal prime contract awards, 37 of which started in 2025 or 2026, mostly with the Army, the Defense Health Agency and the VA.

PET/CT software processes the study: it reconstructs the emission data, registers it to the CT, fuses the two, and produces measurements such as SUVmax that a viewer alone cannot. A PACS stores and displays the finished series. Many departments read PET/CT on the processing workstation and send the fused series and screen captures to the PACS afterward, so the two are bought separately and the PACS integration question is whether the fused output and the measurements arrive intact.

Partly. Processing software can export the measurement table, and structured reporting templates can hold fixed fields for the comparison study, the SUV values and the response category, so the report is assembled rather than dictated from a blank page. Radiological.ai drafts the structured report into the department's own template and reads the CT component of a hybrid study for suspected findings; it does not quantify PET or SPECT data. The physician enters the functional interpretation and reviews, edits and signs every report.

Yes. GE HealthCare agreed to acquire MIM Software on January 8, 2024 and completed the purchase of 100 percent of the stock on April 1, 2024, for approximately $258 million net of cash acquired plus up to $35 million tied to milestones, according to GE HealthCare's quarterly filing. MIM continues to be sold as vendor-neutral software, and its federal contracts still appear under the MIM Software Inc name.

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