Compare · Riverain ClearRead CT

ClearRead CT Alternatives and Lung Nodule CAD Software for Chest CT

The short answer

The main alternatives to ClearRead CT are other FDA-cleared lung CT CAD products under OEB, including Coreline AVIEW Lung Nodule CAD, Infervision InferRead Lung CT.AI, Fujifilm Synapse Lung Nodule AI and Siemens syngo.CT Lung CAD. A different option is a decision-support assistant such as Radiological.ai that covers the whole read by flagging suspected findings, measuring confirmed nodules, comparing the prior and drafting the Lung-RADS report. ClearRead CT is an adjunctive detection layer for screening and surveillance low-dose chest CT in non-oncology patients. Single-site VA orders for ClearRead CT range from $24,000 to $48,750, according to USAspending.gov.

ClearRead CT suppresses vessels on chest CT and flags pulmonary nodules, according to Riverain. The results appear as an extra series in the study, and Riverain says the software works with any CT scanner and PACS. It has a long VA purchasing record behind it, while the ClearRead family also includes X-ray bone suppression. Those are concrete reasons to keep it on a shortlist for lung nodule detection.

The openFDA record contains 20 OEB lung CT CAD clearances in total since 2003, not 20 separate products. Coreline, Infervision, Fujifilm, Siemens, V5med and MeVis offer other products in that category. If the need extends from detection to measurements, prior comparison and report drafting, Radiological.ai supports those steps alongside the existing PACS. It is decision support and makes no FDA clearance claim. The radiologist confirms every nodule, assigns the category and signs.

The Reading Station

Assistant ready

Worklist

Not for diagnostic use

Structured report

Draft

Run the assistant to draft this report for review.

You review & sign

Decision support. The radiologist reviews and signs every study.

Drafted in · you review & sign Worklist re-prioritized

Decision support for qualified clinicians. Radiological.ai does not provide a diagnosis and is not a substitute for professional judgment.

See the comparison

Flag · prioritize · draft · you review and sign

ClearRead CT is a detection layer. Radiological.ai supports the whole read by flagging suspected findings, measuring nodules the radiologist confirms, comparing the matching nodule from the prior and drafting the Lung-RADS report, at $199 per reading radiologist per month billed annually on Practice. It is decision support and makes no FDA clearance claim.

Side by side

ClearRead CT against lung nodule CAD alternatives and reading support

Compare the cleared detection task, integration claims and public purchasing evidence before deciding how much of the read needs support.

What to compare	Riverain ClearRead CT	Lung CT CAD alternatives and Radiological.ai
Detection approach	Riverain says ClearRead CT suppresses vessels on chest CT and then flags nodules, returning an extra series in the study.	Coreline AVIEW Lung Nodule CAD, Infervision InferRead Lung CT.AI, Fujifilm Synapse Lung Nodule AI and Siemens syngo.CT Lung CAD have OEB clearances. Check each product's indication rather than assuming the same approach.
FDA clearance record	ClearRead CT K221612, December 5, 2022, follows K161201, September 9, 2016, both under OEB.	OEB contains 20 clearances in total since 2003, including V5med Lung AI and MeVis Veolity. Radiological.ai is decision support and makes no FDA clearance claim.
Intended use	K221612 covers computer-assisted reading of pulmonary nodules on screening and surveillance low-dose chest CT in non-oncology patients, adjunctive to the original series.	Use the K number for each CAD product to check its scope. Radiological.ai flags suspected findings and leaves nodule confirmation, category assignment and report signing to the radiologist.
Scanner and PACS fit	Riverain describes ClearRead CT as vendor-neutral and compatible with any CT scanner and PACS. Its flyer specifies slice thickness of 3 mm or less.	Radiological.ai works alongside existing PACS over DICOM and returns results over HL7 or FHIR. Confirm the proposed CAD product's requirements with its vendor.
Related product family	The ClearRead family includes X-ray bone suppression, ClearRead Xray Pneumothorax and ClearRead CT CAC. Riverain has 8 clearances across its products, not all under OEB.	Coreline Soft has 12 clearances across AVIEW products. Siemens AI-Rad Companion Pulmonary is a separate JAK product, not an OEB lung CT CAD clearance.
VA purchasing history	Riverain has 92 prime awards, all from the VA, totaling $17,167,903. These cover the wider product family and include X-ray purchases, not just ClearRead CT.	Do not treat the Riverain award total as spending on lung CT CAD alone. Compare the named modules and scope in a quote against the specific ClearRead CT orders.
Price reference	Single-site ClearRead CT orders run $24,000 to $48,750. Multi-module or regional ClearRead orders run $97,500 to $246,790. These are VA orders, not a price list.	No vendor in the lung CT CAD category publishes a price list. Radiological.ai Practice covers X-ray and CT at $199 per reading radiologist per month billed annually, or $399 month to month.
Support through the report	ClearRead CT provides an adjunctive detection series. The original CT series remains part of the read.	Radiological.ai measures confirmed nodules, pulls the matching nodule from the prior, prioritizes the worklist and drafts a Lung-RADS or house-template report with the nodule table populated.

Sources are the openFDA 510(k) database and USAspending.gov, collected October 20, 2026. Product descriptions and scanner compatibility are vendor-stated. VA orders are purchasing references, not published list prices.

What the public record shows

The FDA record for lung CT CAD software

OEB is the class II product code for lung computed tomography computer-aided detection under 21 CFR 892.2050. Its 20 clearances include repeat submissions for the same products.

Product	Most recent OEB 510(k) found	What the record establishes
Riverain ClearRead CT	K221612, December 5, 2022	Earlier OEB clearance K161201, September 9, 2016. The K221612 indication covers adjunctive reading of pulmonary nodules on screening and surveillance low-dose chest CT in non-oncology patients.
Coreline AVIEW Lung Nodule CAD	K251203, December 3, 2025	Earlier OEB clearance K221592, February 24, 2023. Coreline Soft has 12 clearances across AVIEW, AVIEW LCS, AVIEW CAC and AVIEW Lung Nodule CAD.
Infervision InferRead Lung CT.AI	K240554, May 16, 2025	Earlier OEB clearance K192880, July 2, 2020. Both records belong to the lung CT CAD category.
Fujifilm Synapse Lung Nodule AI	K254075, May 27, 2026	An OEB clearance under Fujifilm Corporation for Synapse Lung Nodule AI.
Siemens syngo.CT Lung CAD	K231157, July 19, 2023	The VD30 clearance follows K203258 in 2021, K193216 in 2020 and K143196 in 2015. AI-Rad Companion Pulmonary is separate and falls under JAK, not OEB.
V5med Lung AI	K242919, March 27, 2025	An OEB clearance under V5med, Inc. for V5med Lung AI.
MeVis Veolity	K201501, February 23, 2021	An OEB clearance under MeVis Medical Solutions AG for Veolity.
Aidence Veye Lung Nodules	No record found under Aidence or Veye	Now part of DeepHealth. In openFDA, we found no FDA 510(k) record under that name; ask the vendor for the K number.

Sources are the openFDA 510(k) database and USAspending.gov, collected October 20, 2026. Clearance entries below are from openFDA. VA order benchmarks elsewhere on this page are from USAspending.gov. No record under a searched name is not proof of no clearance.

Side by side

Radiological.ai vs Riverain ClearRead CT, honestly

A fair look at what each does well. Both are capable tools. Here is where they differ.

What matters	Radiological.ai	Riverain ClearRead CT
Role in the read	Decision support that flags suspected findings, measures confirmed nodules, compares the prior, prioritizes the worklist and drafts the structured report.	A detection layer that suppresses vessels and flags nodules on chest CT, according to Riverain.
Nodule measurements and prior	Places diameter and volume measurements on nodules the radiologist confirms and pulls the matching nodule from the prior study.	Riverain's published material centers on vessel suppression and nodule flagging. Ask for a demo of any measurement or prior comparison step you need before you sign.
Report and responsibility	Drafts Lung-RADS or a house template with the nodule table populated. The radiologist confirms every nodule, assigns the category and signs.	K221612 describes adjunctive computer-assisted reading. The extra series does not replace the original CT series.
Integration	Works alongside existing PACS over DICOM, with results returned over HL7 or FHIR.	Riverain says ClearRead CT works with any CT scanner and PACS and delivers its results as an extra series.
Cost reference	Practice covers X-ray and CT for $199 per reading radiologist per month billed annually, or $399 month to month.	No published price list. Single-site VA ClearRead CT orders range from $24,000 to $48,750, with scope specific to each order.
Regulatory record and strengths	Decision support with no FDA clearance claim. Supports the steps from suspected findings through a draft report for radiologist review.	OEB clearances since 2016, a long VA record, vendor-neutral vessel suppression and X-ray bone suppression in the wider ClearRead family.

Comparison reflects general, publicly understood positioning. Capabilities change, so check each product for the latest.

For the steps from a suspected nodule through measurements, prior comparison and the report, see AI lung nodule detection and the lung cancer screening workflow. Radiological.ai drafts the Lung-RADS report, while the radiologist confirms the nodules and assigns the category.

The lung nodule AI software cost analysis examines the public purchasing benchmarks alongside the clearance record. Compare those order-specific amounts with the published per-radiologist plans on pricing, and use the radiology AI regulatory guide when checking a vendor's K number.

Review PACS integration for the DICOM connection and HL7 or FHIR results, and structured radiology reporting for draft reports. If the evaluation includes the wider ClearRead family, chest X-ray decision support describes our assistant's role on that modality.

Why groups pick Radiological.ai

One assistant across the whole read

Start with the cleared indication

ClearRead CT K221612 is adjunctive software for screening and surveillance low-dose chest CT in non-oncology patients. Ask each CAD vendor for the K number and indication that cover your planned use. A JAK clearance for a CT system is not an OEB lung CT CAD clearance.

Keep the vessel suppression advantage in view

Riverain describes vessel suppression followed by nodule flagging, delivered as an extra series in the existing study. Its vendor-neutral positioning, long VA record and X-ray bone suppression family are reasons to consider ClearRead. Check the stated slice thickness of 3 mm or less against your protocols.

Read the order scope before comparing prices

Single-site VA ClearRead CT orders of $24,000 to $48,750 differ from multi-module or regional ClearRead orders of $97,500 to $246,790. Neither range is a list price or an annual subscription quote. Compare the licensed modules, coverage period, support and maintenance in the actual order.

Evaluate the work after the flag

Radiological.ai places diameter and volume measurements on confirmed nodules, pulls the matching prior nodule and drafts the Lung-RADS or house-template report. It also prioritizes the worklist. The radiologist confirms every nodule, assigns the category and signs. Practice pricing is per reading radiologist, with X-ray and CT included.

Good questions

Riverain ClearRead CT vs Radiological.ai, answered

The direct alternatives are FDA-cleared OEB lung CT CAD products including Coreline AVIEW Lung Nodule CAD, Infervision InferRead Lung CT.AI, Fujifilm Synapse Lung Nodule AI and Siemens syngo.CT Lung CAD. V5med Lung AI and MeVis Veolity also have OEB records. Radiological.ai is a different option for decision support through measurements, prior comparison and report drafting, without an FDA clearance claim.

Yes, ClearRead CT has FDA 510(k) clearances K161201 from 2016 and K221612 from 2022 under product code OEB. The K221612 indication covers computer-assisted reading of pulmonary nodules on screening and surveillance low-dose chest CT in non-oncology patients. It is adjunctive software and does not replace the original CT series.

Single-site VA ClearRead CT orders range from $24,000 to $48,750 in USAspending.gov records. Riverain does not publish a price list, so these purchases are benchmarks rather than quotes for your site. Multi-module or regional ClearRead orders range from $97,500 to $246,790. Check the modules, coverage period, maintenance and support before comparing an offer with those orders.

ClearRead CT Vessel Suppress suppresses vessels on chest CT, according to Riverain. Riverain describes a workflow that suppresses vessels and then flags nodules, with results appearing as an extra series in the study. Its flyer specifies slice thickness of 3 mm or less. The output is adjunctive, so the radiologist still reads the original CT series.

Riverain says ClearRead CT works with any CT scanner and PACS. It returns results as an extra series within the study, and the vendor flyer specifies slice thickness of 3 mm or less. Treat compatibility as a vendor claim to verify against your actual scanner protocols and PACS configuration during evaluation.

OEB clearances include ClearRead CT, Coreline AVIEW Lung Nodule CAD, Infervision InferRead Lung CT.AI, Fujifilm Synapse Lung Nodule AI, Siemens syngo.CT Lung CAD, V5med Lung AI and MeVis Veolity. The database contains 20 OEB clearances in total since 2003, including repeat submissions. For Aidence Veye, we found no FDA 510(k) record under that name; ask the vendor for the K number.

Yes, an AI reading assistant can support the read alongside ClearRead CT. Radiological.ai works with existing PACS over DICOM, measures confirmed nodules, pulls the matching prior nodule and drafts a Lung-RADS or house-template report. Results return over HL7 or FHIR. It is decision support without an FDA clearance claim; the radiologist confirms nodules, assigns the category and signs.

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See how Radiological.ai reads alongside your group

One assistant that flags suspected findings, prioritizes the worklist, and drafts the structured report on X-ray, CT and MRI. You review and sign every study.

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Decision support for qualified clinicians. Radiological.ai does not provide a diagnosis and is not a substitute for professional medical judgment.